The options available extend from hotels and villas to 'agriturismos' and, for the brave, camping!

Hotels:
There are three towns around Tuoro wth nice hotels, Cortona to the north-west, Castiglione del Lago to the south and Passignano to the east. (Note: Tuoro is half-covered by the red '1' marker on the map)
Sanguineto3
Cortona, across the Tuscan border, offers these 4-star hotels: San Michele, San Luca, Corys, Borga Il Melone, Relais Petrischio, La Corte Dei Papi, and...

Castiglione offers 8 3-star hotels: Aganoor, Duca Dela Corgna, La Torre, Le Macerine, Locanda Poggio Leone, Miralago, Regina Di Cuori, and Trasimeno, and the 2-stars Dependance Villa La Torre.

Tuoro itself has very little in the way of hotels to.